Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639510 | 0.81 | HTR2A (0.50) | NPSR1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19623475 | 0.80 | ACHE (0.51) | NPSR1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14731022 | 0.80 | MAPT (0.42) | NPSR1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19623881 | 0.78 | HTR2A (0.38) | NPSR1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14731120 | 0.77 | MAPT (0.44) | NPSR1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19623495 | 0.77 | KDM4E (0.57) | NPSR1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL24725927 | 0.77 | MAPT (0.47) | NPSR1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14731124 | 0.76 | MAPT (0.43) | NPSR1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16682856 | 0.74 | MAPT (0.45) | NPSR1MAPTNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL16669168 | 0.72 | MAPT (0.44) | NPSR1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050749-B1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2017-11-22 | — | — | EP | disclosed |