Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.55 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.51 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2377056 | 0.92 | PIK3CA (0.56) | PIK3CAPIK3R1MTORGAAMAPT | |
| SCHEMBL2377364 | 0.84 | PIK3CA (0.63) | PIK3CAPIK3R1MTOR | |
| SCHEMBL2377693 | 0.83 | PIK3CA (0.67) | PIK3CAPIK3R1MTOR | |
| SCHEMBL2376634 | 0.82 | PIK3CA (0.73) | PIK3CAPIK3R1 | |
| SCHEMBL3224544 | 0.81 | PIK3CA (0.71) | PIK3CAPIK3R1MTOR | |
| SCHEMBL2377490 | 0.81 | PIK3CA (0.61) | PIK3CAPIK3R1MTOR | |
| SCHEMBL19623429 | 0.80 | PIK3CA (0.58) | PIK3CAPIK3R1 | |
| SCHEMBL27760031 | 0.80 | PIK3CA (0.67) | PIK3CAPIK3R1MTOR | |
| SCHEMBL2378462 | 0.80 | PIK3CA (0.60) | PIK3CAPIK3R1 | |
| SCHEMBL2376941 | 0.79 | PIK3CA (0.64) | PIK3CAPIK3R1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050749-B1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2017-11-22 | — | — | EP | disclosed |