Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19499898 | 0.98 | ELANE (0.39) | HTTTDP1POLBAPEX1ELANE | |
| SCHEMBL21891667 | 0.94 | TDP1 (0.41) | HTTTDP1POLBAPEX1ELANE | |
| SCHEMBL17485637 | 0.94 | POLB (0.44) | HTTTDP1POLBAPEX1ELANE | |
| SCHEMBL21675423 | 0.93 | POLB (0.43) | HTTTDP1POLBAPEX1ELANE | |
| SCHEMBL18808109 | 0.91 | HTT (0.40) | HTTTDP1POLBAPEX1ELANE | |
| SCHEMBL21254298 | 0.90 | POLB (0.41) | HTTTDP1POLBAPEX1ELANE | |
| SCHEMBL22072003 | 0.89 | POLB (0.39) | HTTTDP1POLBAPEX1ELANE | |
| SCHEMBL21693481 | 0.89 | POLB (0.40) | HTTTDP1POLBAPEX1ELANE | |
| SCHEMBL26713083 | 0.89 | TDP1 (0.37) | HTTTDP1POLBAPEX1ELANE | |
| SCHEMBL20032595 | 0.88 | POLB (0.39) | HTTTDP1POLBAPEX1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126567-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2024-06-20 | — | — | WO | disclosed |
| EP-3246377-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |