Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17485637 | 0.94 | POLB (0.44) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL21675423 | 0.93 | POLB (0.43) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL20032596 | 0.91 | TDP1 (0.36) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL21254298 | 0.90 | POLB (0.41) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL22072003 | 0.89 | POLB (0.39) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL21693481 | 0.89 | POLB (0.40) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19624269 | 0.88 | HTT (0.42) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL29333409 | 0.88 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL25933597 | 0.88 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL25943857 | 0.87 | POLB (0.36) | POLBAPEX1HTTTDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938229-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9938229-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |