Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568773 | 0.85 | KMT2A (0.49) | KMT2AL3MBTL1ALDH1A1MAPK1 | |
| 1,4-Dipropoxybenzene SCHEMBL122039 | 0.80 | LTA4H (0.67) | LTA4HCA12CA1CA2CA7 | |
| SCHEMBL13808346 | 0.78 | LTA4H (0.64) | LTA4HCA12CA1CA2CA7 | |
| SCHEMBL13464271 | 0.77 | CYP2C9 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18088219 | 0.77 | USP2 (0.42) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL19624369 | 0.77 | USP2 (0.43) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL7929606 | 0.76 | LTA4H (0.48) | LTA4HCA12CA1CA2CA7 | |
| SCHEMBL13845205 | 0.76 | FFAR1 (0.50) | LTA4HCA12CA1CA2CA7 | |
| 1-Butyloxy-4-Propoxybenzene SCHEMBL23828869 | 0.75 | LTA4H (0.64) | LTA4HCA12CA1CA2CA7 | |
| 1,4-Dipropoxybenzene SCHEMBL10846150 | 0.75 | LTA4H (0.64) | LTA4HCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246330-A1 | IMIDAZOLES AS HISTONE DEMETHYLASE INHIBITORS | Istituto Europeo di Oncologia S.r.l. (IT) | 2017-11-22 | — | — | EP | disclosed |