Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22592354 | 0.97 | ELANE (0.40) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL23397388 | 0.93 | POLB (0.38) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL23350755 | 0.93 | POLB (0.38) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL24170705 | 0.93 | POLB (0.38) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL18487848 | 0.93 | POLB (0.38) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL16559864 | 0.89 | POLB (0.43) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL15180381 | 0.89 | POLB (0.43) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL26142346 | 0.89 | ELANE (0.38) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL21102080 | 0.87 | POLB (0.43) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL16559835 | 0.87 | POLB (0.43) | ELANEPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3730591-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| US-10472569-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-11-12 | — | — | US | disclosed |
| EP-3246377-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |