Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 11/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18487848 | 1.00 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL23350755 | 1.00 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL26142346 | 0.96 | ELANE (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL23397388 | 0.94 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19624400 | 0.93 | ELANE (0.41) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL16559864 | 0.92 | POLB (0.43) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL15180381 | 0.92 | POLB (0.43) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL21087700 | 0.90 | POLB (0.33) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL22592354 | 0.90 | ELANE (0.40) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL21102080 | 0.90 | POLB (0.43) | POLBAPEX1HTTTDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022003001-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2022-01-06 | — | — | WO | disclosed |