Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | RARB | P10826 | 7/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19624536 | 0.92 | MAPK1 (0.39) | THRBRARBRARARARGMAPK1 | |
| SCHEMBL19624673 | 0.89 | HTT (0.41) | THRBRARBRARARARGMAPK1 | |
| SCHEMBL19797143 | 0.88 | HTT (0.41) | THRBMAPK1HTTMAPTPTPN1 | |
| SCHEMBL19796621 | 0.88 | HTT (0.42) | THRBRARBRARARARGMAPK1 | |
| SCHEMBL19796256 | 0.87 | THRB (0.44) | THRBRARBRARARARGMAPK1 | |
| SCHEMBL17070363 | 0.83 | CNR2 (0.39) | THRBRARBRARARARGMAPK1 | |
| SCHEMBL19624416 | 0.83 | PDE4A (0.36) | RARBRARARARGHTTESR1 | |
| SCHEMBL19624679 | 0.83 | HTT (0.38) | THRBRARBRARARARGMAPK1 | |
| SCHEMBL19797152 | 0.83 | MEN1 (0.37) | THRBRARBRARARARGMAPK1 | |
| SCHEMBL19796634 | 0.83 | MAPT (0.43) | THRBRARBRARARARGMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246305-A1 | COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2017-11-22 | — | — | EP | disclosed |