Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.52 |
| ▸ | EGFR | P00533 | 4/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | ITK | Q08881 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25060294 | 0.98 | BTK (0.49) | BTKEGFRSRCLCKITK | |
| SCHEMBL25060477 | 0.95 | BTK (0.48) | BTKEGFRLCK | |
| SCHEMBL20411963 | 0.90 | BTK (0.52) | BTKEGFRSRCLCKITK | |
| SCHEMBL15756453 | 0.89 | BTK (0.57) | BTKEGFRSRCLCKITK | |
| SCHEMBL15756452 | 0.89 | BTK (0.57) | BTKEGFRSRCLCKITK | |
| SCHEMBL19624892 | 0.86 | BTK (0.52) | BTKEGFRSRCLCKITK | |
| SCHEMBL15756479 | 0.86 | BTK (0.49) | BTKEGFRSRCLCKITK | |
| SCHEMBL15756458 | 0.85 | BTK (0.48) | BTKEGFRSRCLCKITK | |
| SCHEMBL19624681 | 0.85 | PIK3CD (0.39) | BTK | |
| SCHEMBL19544659 | 0.85 | BTK (0.55) | BTKEGFRSRCLCKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |