Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.52 |
| ▸ | EGFR | P00533 | 4/20 | 0.48 |
| ▸ | TEC | P42680 | 3/20 | 0.46 |
| ▸ | BMX | P51813 | 3/20 | 0.46 |
| ▸ | TXK | P42681 | 2/20 | 0.46 |
| ▸ | LYN | P07948 | 2/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.46 |
| ▸ | ITK | Q08881 | 2/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.46 |
| ▸ | LATS1 | O95835 | 1/20 | 0.46 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | YES1 | P07947 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19624445 | 0.94 | BTK (0.51) | BTKEGFRLCK | |
| SCHEMBL25060294 | 0.89 | BTK (0.49) | BTKEGFRITKLCKSRC | |
| SCHEMBL19624641 | 0.86 | BTK (0.52) | BTKEGFRITKLCKSRC | |
| SCHEMBL25060477 | 0.83 | BTK (0.48) | BTKEGFRLCK | |
| SCHEMBL19624840 | 0.82 | BTK (0.52) | BTKEGFRFLT3 | |
| SCHEMBL20411964 | 0.81 | BTK (0.62) | BTKEGFRSRC | |
| SCHEMBL19624642 | 0.80 | BTK (0.51) | BTKEGFRTECBMXTXK | |
| SCHEMBL19533629 | 0.80 | BTK (0.49) | BTKEGFRFLT3 | |
| SCHEMBL20411963 | 0.80 | BTK (0.52) | BTKEGFRITKLCKSRC | |
| SCHEMBL19533529 | 0.80 | BTK (0.55) | BTKEGFRITKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |