Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464533 | 0.87 | HSD11B1 (0.40) | HSD11B1BUB1BTKASGR1KAT6A | |
| SCHEMBL26667530 | 0.87 | HSD11B1 (0.40) | HSD11B1BUB1BTKASGR1KAT6A | |
| Hydrochloric Acid SCHEMBL7419816 | 0.86 | HSD11B1 (0.40) | HSD11B1BUB1BTKASGR1KAT6A | |
| Hydrochloric Acid SCHEMBL8184993 | 0.86 | HSD11B1 (0.40) | HSD11B1BUB1BTKASGR1KAT6A | |
| SCHEMBL190837 | 0.85 | HSD11B1 (0.47) | HSD11B1BUB1ASGR1KAT6AKAT8 | |
| SCHEMBL5270126 | 0.80 | HSD11B1 (0.41) | HSD11B1BUB1BTKASGR1KAT6A | |
| SCHEMBL28804055 | 0.80 | HSD11B1 (0.44) | HSD11B1BUB1ASGR1KAT6AKAT8 | |
| SCHEMBL28804053 | 0.80 | HSD11B1 (0.44) | HSD11B1BUB1ASGR1KAT6AKAT8 | |
| SCHEMBL228179 | 0.79 | HSD11B1 (0.46) | HSD11B1BTKASGR1KDM4DGAA | |
| SCHEMBL1344888 | 0.79 | HSD11B1 (0.41) | HSD11B1BUB1BTKASGR1KDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |