Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19533708 | 0.81 | PARP1 (0.36) | FGFR1KCNH2 | |
| SCHEMBL19544846 | 0.71 | PARP1 (0.36) | FGFR1 | |
| SCHEMBL19533293 | 0.67 | JAK1 (0.36) | FGFR1KCNH2 | |
| SCHEMBL19544911 | 0.66 | PDPK1 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL23122495 | 0.65 | PARP1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL19533307 | 0.64 | FGFR1 (0.39) | FGFR1KCNH2KDM4EALDH1A1 | |
| SCHEMBL19533303 | 0.61 | PRMT5 (0.33) | FGFR1KCNH2ALDH1A1 | |
| SCHEMBL23121627 | 0.61 | ALDH1A1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL23122198 | 0.61 | PARP1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL19533304 | 0.60 | JAK1 (0.34) | FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |