Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 11/20 | 0.54 |
| ▸ | AURKA | O14965 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | BTK | Q06187 | 2/20 | 0.44 |
| ▸ | ITK | Q08881 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | LYN | P07948 | 1/20 | 0.44 |
| ▸ | TEC | P42680 | 1/20 | 0.44 |
| ▸ | TXK | P42681 | 1/20 | 0.44 |
| ▸ | BMX | P51813 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | CD69 | Q07108 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19544927 | 0.88 | SYK (0.57) | SYKAURKANPC1MAPTEGFR | |
| SCHEMBL18198827 | 0.75 | SYK (0.54) | SYKAURKAEGFRBTKITK | |
| SCHEMBL22909438 | 0.74 | SYK (0.56) | SYKAURKAEGFRBTKITK | |
| SCHEMBL29729055 | 0.74 | SYK (0.56) | SYKAURKAEGFRBTKITK | |
| SCHEMBL23408964 | 0.74 | SYK (0.68) | SYKAURKAEGFRBTKITK | |
| SCHEMBL25068921 | 0.73 | SYK (0.64) | SYKAURKAEGFRBTKITK | |
| SCHEMBL25068908 | 0.72 | SYK (0.57) | SYKAURKAEGFRBTKITK | |
| SCHEMBL23409017 | 0.72 | SYK (0.68) | SYKAURKAEGFRBTKITK | |
| SCHEMBL22909543 | 0.72 | SYK (0.69) | SYKAURKAEGFRBTKITK | |
| SCHEMBL25069047 | 0.71 | SYK (0.60) | SYKAURKAEGFRBTKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |