Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 10/20 | 0.68 |
| ▸ | AURKA | O14965 | 3/20 | 0.67 |
| ▸ | EGFR | P00533 | 7/20 | 0.63 |
| ▸ | ITK | Q08881 | 3/20 | 0.63 |
| ▸ | BTK | Q06187 | 2/20 | 0.63 |
| ▸ | JAK2 | O60674 | 1/20 | 0.63 |
| ▸ | LYN | P07948 | 1/20 | 0.63 |
| ▸ | TEC | P42680 | 1/20 | 0.63 |
| ▸ | TXK | P42681 | 1/20 | 0.63 |
| ▸ | BMX | P51813 | 1/20 | 0.63 |
| ▸ | JAK3 | P52333 | 1/20 | 0.63 |
| ▸ | CD69 | Q07108 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25068921 | 0.93 | SYK (0.64) | SYKAURKAEGFRITKBTK | |
| SCHEMBL30150629 | 0.91 | SYK (0.77) | SYKAURKAEGFRITKBTK | |
| SCHEMBL23388258 | 0.91 | SYK (0.77) | SYKAURKAEGFRITKBTK | |
| SCHEMBL23408964 | 0.91 | SYK (0.68) | SYKAURKAEGFRITKBTK | |
| SCHEMBL22909543 | 0.91 | SYK (0.69) | SYKAURKAEGFRITKBTK | |
| SCHEMBL25069015 | 0.88 | SYK (0.68) | SYKAURKAEGFRITKBTK | |
| SCHEMBL25069016 | 0.87 | SYK (0.64) | SYKAURKAEGFRITKBTK | |
| SCHEMBL25068907 | 0.87 | SYK (0.64) | SYKAURKAEGFRITKBTK | |
| SCHEMBL21443531 | 0.86 | EGFR (0.72) | SYKAURKAEGFRITKBTK | |
| SCHEMBL28704792 | 0.85 | EGFR (0.66) | SYKAURKAEGFRITKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |