Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.47 |
| ▸ | BHMT | Q93088 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.46 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL1962486 | 1.00 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2SLC1A1BHMT | |
| Aspartic Acid SCHEMBL22092469 | 0.93 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1BHMT | |
| Aspartic Acid SCHEMBL464907 | 0.93 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1BHMT | |
| Aspartic Acid SCHEMBL464908 | 0.93 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1BHMT | |
| Aspartic Acid SCHEMBL939864 | 0.93 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1BHMT | |
| Aspartic Acid SCHEMBL23454434 | 0.93 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1BHMT | |
| Aspartic Acid SCHEMBL6419228 | 0.91 | GLRA1 (0.53) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Aspartic Acid SCHEMBL7717425 | 0.91 | GLRA1 (0.53) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Aspartic Acid SCHEMBL307008 | 0.91 | GLRA1 (0.53) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Aspartic Acid SCHEMBL8074635 | 0.91 | GLRA1 (0.53) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110169590-B | Process control method for nicotine content of bagged buccal smokeless tobacco product | 云南中烟工业有限责任公司 | 2021-09-14 | — | — | CN | disclosed |
| WO-2011072264-A2 | METHODS AND COMPOSITIONS FOR BIOMASS TREATMENT | QTEROS, INC. (US) | 2011-06-16 | — | — | WO | disclosed |
| EP-1891107-A2 | COMPOSITIONS AND METHODS FOR MODULATING IMMUNE RESPONSES | ZymoGenetics, Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006124667-A2 | COMPOSITIONS AND METHODS FOR MODULATING IMMUNE RESPONSES | ZYMOGENETICS, INC. (US) | 2006-11-23 | — | — | WO | disclosed |
| EP-1165833-A1 | METHODS AND COMPOSITIONS USING BINDING PARTNERS | Cyclacel Limited (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000050635-A1 | METHODS AND COMPOSITIONS USING BINDING PARTNERS | CYCLACEL LIMITED (GB) | 2000-08-31 | — | — | WO | disclosed |