Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 5/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.37 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19544722 | 1.00 | BTK (0.46) | BTKPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL19544304 | 0.88 | BTK (0.48) | BTKPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL25060355 | 0.88 | BTK (0.48) | BTKPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL19624818 | 0.87 | BTK (0.51) | BTKALDH1A1GPR119HPGDKDM4E | |
| SCHEMBL19544600 | 0.87 | BTK (0.51) | BTKALDH1A1GPR119HPGDKDM4E | |
| SCHEMBL25060481 | 0.87 | BTK (0.38) | BTKPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL19544647 | 0.86 | BTK (0.55) | BTKEGFR | |
| SCHEMBL19544659 | 0.86 | BTK (0.55) | BTKEGFR | |
| SCHEMBL19624681 | 0.85 | PIK3CD (0.39) | BTKPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL19544682 | 0.84 | BTK (0.48) | BTKALDH1A1GPR119HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |