Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.40 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25060355 | 0.88 | BTK (0.48) | ABL1RIN1BTKMEN1KMT2A | |
| SCHEMBL19544304 | 0.88 | BTK (0.48) | ABL1RIN1BTKMEN1KMT2A | |
| SCHEMBL19624846 | 0.81 | CHEK2 (0.45) | BTKGPR119 | |
| SCHEMBL19624840 | 0.80 | BTK (0.52) | BTKEGFR | |
| SCHEMBL19544599 | 0.80 | CHEK2 (0.43) | BTKGPR119 | |
| SCHEMBL19545099 | 0.78 | BTK (0.51) | BTKEGFR | |
| SCHEMBL19533648 | 0.78 | BTK (0.44) | ABL1RIN1BTKMEN1KMT2A | |
| SCHEMBL19624953 | 0.78 | CHEK2 (0.42) | BTKGPR119 | |
| SCHEMBL19624818 | 0.78 | BTK (0.51) | BTKGPR119 | |
| SCHEMBL19533629 | 0.78 | BTK (0.49) | BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |