Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | NPM1 | P06748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180229 | 0.85 | MEN1 (0.40) | ALKLMNAALOX12HPGDNPC1 | |
| SCHEMBL26495850 | 0.83 | MAPT (0.41) | LMNAALOX12HPGDNPC1RAB9A | |
| SCHEMBL19057601 | 0.83 | LMNA (0.46) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL24153497 | 0.83 | MEN1 (0.41) | LMNAALOX12HPGDNPC1RAB9A | |
| SCHEMBL21371366 | 0.83 | ALK (0.45) | ALKLMNAALOX12HPGDNPC1 | |
| SCHEMBL20180309 | 0.81 | ABCG2 (0.41) | ALKLMNAALOX12HPGDMEN1 | |
| SCHEMBL24185261 | 0.79 | MAPT (0.39) | ALKLMNAALOX12HPGDNPC1 | |
| SCHEMBL20180549 | 0.78 | EGFR (0.47) | LMNAALOX12HPGDMEN1KMT2A | |
| SCHEMBL29940289 | 0.77 | MAPT (0.50) | LMNAALOX12HPGDNPC1RAB9A | |
| SCHEMBL14428159 | 0.76 | ALK (0.51) | ALKLMNAALOX12HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |