Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17758015 | 0.92 | TDP1 (0.51) | TDP1PDE7AMEN1KMT2ATTR | |
| SCHEMBL10686176 | 0.76 | TDP1 (0.63) | TDP1PDE7AMEN1KMT2ATTR | |
| SCHEMBL26758044 | 0.73 | TDP1 (0.62) | TDP1PDE7AMEN1KMT2ATTR | |
| SCHEMBL10495381 | 0.71 | TDP1 (0.60) | TDP1PDE7AMEN1KMT2ATTR | |
| SCHEMBL11152276 | 0.70 | TDP1 (0.67) | TDP1PDE7AMEN1KMT2ATTR | |
| SCHEMBL10851196 | 0.70 | TDP1 (0.67) | TDP1PDE7AMEN1KMT2ATTR | |
| SCHEMBL27894847 | 0.70 | TDP1 (0.62) | TDP1PDE7AMEN1KMT2ATTR | |
| SCHEMBL10847574 | 0.69 | TDP1 (0.65) | TDP1PDE7AMEN1KMT2ATTR | |
| SCHEMBL10881418 | 0.68 | TDP1 (0.61) | TDP1PDE7AMEN1KMT2ATTR | |
| Potassium Ion SCHEMBL11543008 | 0.68 | TDP1 (0.74) | TDP1PDE7AMEN1KMT2ATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198693-A1 | A COMPOSITION COMPRISING MESOPOROUS SILICON DIOXIDE PARTICLES AND A NITRIFICATION INHIBITOR | BASF SE (DE) | 2017-11-23 | — | — | WO | disclosed |