SCHEMBL19625540

SCHEMBL19625540

Cc1cc(C)c(/N=C2C(=N/c3c(C(C)C)cccc3C(C)C)/c3cccc4cccc/2c34)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KCNN2 Q9H2S1 5/20 0.34
KCNN3 Q9UGI6 5/20 0.34
LMNA P02545 2/20 0.33
ALDH1A1 P00352 4/20 0.33
TSHR P16473 3/20 0.33
MAPK1 P28482 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CASP1 P29466 2/20 0.33
CASP7 P55210 2/20 0.33
HPGD P15428 2/20 0.33
HIF1A Q16665 2/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
USP1 O94782 1/20 0.31
WDR48 Q8TAF3 1/20 0.31
CYP1A2 P05177 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5589772 0.90 POLB (0.40) MEN1KMT2AKCNN2KCNN3LMNA
SCHEMBL5589365 0.88 POLB (0.39) MEN1KMT2AKCNN2KCNN3LMNA
SCHEMBL12304879 0.88 MEN1 (0.50) MEN1KMT2ALMNAALDH1A1TSHR
SCHEMBL21114848 0.88 MEN1 (0.50) MEN1KMT2ALMNAALDH1A1TSHR
SCHEMBL5138932 0.88 ALDH1A1 (0.40) MEN1KMT2AKCNN2KCNN3LMNA
SCHEMBL987736 0.88 ALDH1A1 (0.40) MEN1KMT2AKCNN2KCNN3LMNA
SCHEMBL12923294 0.88 ALDH1A1 (0.40) MEN1KMT2AKCNN2KCNN3LMNA
SCHEMBL987735 0.88 ALDH1A1 (0.40) MEN1KMT2AKCNN2KCNN3LMNA
SCHEMBL15624649 0.87 KCNN2 (0.33) MEN1KMT2AKCNN2KCNN3ALDH1A1
SCHEMBL19625542 0.87 POLB (0.37) MEN1KMT2AKCNN2KCNN3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11332552-B2 Low pressure process for preparing low-density polyethylene CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2022-05-17 US disclosed
US-10961331-B2 Ethylene homopolymers with a reverse short chain branch distribution CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2021-03-30 US disclosed
WO-2020131442-A1 ETHYLENE HOMOPOLYMERS WITH A REVERSE SHORT CHAIN BRANCH DISTRIBUTION CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2020-06-25 WO disclosed
US-20200199265-A1 Ethylene Homopolymers with a Reverse Short Chain Branch Distribution CHEVRON PHILLIPS CHEMICAL COMPANY LP 2020-06-25 US disclosed
US-20170335022-A1 LOW PRESSURE PROCESS FOR PREPARING LOW-DENSITY POLYETHYLENE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-11-23 US disclosed
US-20170335022-A1 LOW PRESSURE PROCESS FOR PREPARING LOW-DENSITY POLYETHYLENE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-11-23 US disclosed