SCHEMBL1962597

SCHEMBL1962597

CCCCOC(=O)c1c(O)c(-c2ccccc2)c(CCCC)c(CCCC)c1CCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.52
EGFR P00533 1/20 0.49
TSHR P16473 6/20 0.48
TDP1 Q9NUW8 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
ESR1 P03372 4/20 0.46
LMNA P02545 4/20 0.46
MAPK1 P28482 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2D6 P10635 1/20 0.46
NR1H2 P55055 1/20 0.46
RNASEL Q05823 1/20 0.46
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27543864 0.90 CNR2 (0.52) CNR2EGFRTSHRTDP1L3MBTL1
SCHEMBL16993816 0.78 LMNA (0.43) CNR2EGFRTSHRTDP1LMNA
SCHEMBL5589592 0.76 GCGR (0.46) CNR2TSHRLMNAMAPK1ALDH1A1
SCHEMBL5589600 0.75 PDE4A (0.44) CNR2ESR1LMNASMN1; SMN2ALDH1A1
SCHEMBL27562768 0.74 DPP4 (0.43) CNR2TDP1LMNASMN1; SMN2ALDH1A1
SCHEMBL6762353 0.73 ESR1 (0.58) CNR2TSHRTDP1L3MBTL1ESR1
SCHEMBL5589821 0.73 DPP4 (0.45) CNR2ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL27876741 0.72 GCGR (0.49) CNR2TSHRCYP1A2ALDH1A1KDM4E
SCHEMBL12832705 0.72 TSHR (0.68) CNR2TSHRTDP1L3MBTL1ESR1
SCHEMBL1962594 0.72 MAPT (0.43) MAPK1CYP1A2CYP2C19CYP2D6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170014314-A1 LIQUID COSMETIC COMPOSITION SUITABLE FOR CHANGING TEMPORARILY KERATINIC FIBERS COLOR - RELATED METHOD BBR (FR) 2017-01-19 US claimed
EP-3104830-A1 LIQUID COSMETIC COMPOSITION CAPABLE OF TEMPORARILY MODIFYING THE COLOUR OF KERATIN FIBRES - ASSOCIATED PROCESS BBR (FR) 2016-12-21 EP claimed
WO-2015118276-A1 LIQUID COSMETIC COMPOSITION CAPABLE OF TEMPORARILY MODIFYING THE COLOUR OF KERATIN FIBRES - ASSOCIATED PROCESS BBR (FR) 2015-08-13 WO claimed
US-20120171156-A1 METHODS AND COMPOUNDS FOR REDUCING ALLERGIC REACTIONS TO HAIR DYES HDS LTD. (GB) 2012-07-05 US claimed
EP-2442873-A2 METHODS AND COMPOUNDS FOR REDUCING ALLERGIC REACTIONS TO HAIR DYES Hds Limited (GB) 2012-04-25 EP claimed
WO-2010146142-A9 METHODS AND COMPOUNDS FOR REDUCING ALLERGIC REACTIONS TO HAIR DYES HDS LIMITED (GB) 2011-06-16 WO claimed
WO-2010146142-A2 METHODS AND COMPOUNDS FOR REDUCING ALLERGIC REACTIONS TO HAIR DYES HDS LIMITED (GB) 2010-12-23 WO claimed
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US disclosed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP disclosed
WO-2022221354-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-10-20 WO disclosed
EP-2800608-B1 PERSONAL CARE COMPOSITIONS CONTAINING END-FUNCTIONALIZED IONIC SILICONE MOMENTIVE PERFORMANCE MAT INC (US) 2019-03-13 EP disclosed
EP-2800551-B1 PERSONAL CARE COMPOSITIONS CONTAINING IONIC SILICONE AND FILM-FORMING AGENT MOMENTIVE PERFORMANCE MAT INC (US) 2019-03-13 EP disclosed
US-9895307-B2 Personal care compositions containing ionic silicone and film-forming agent MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-02-20 US disclosed
US-20070009474-A1 Personal care compositions and methods for the beautification of mammalian skin and hair THE PROCTER & GAMBLE COMPANY 2007-01-11 US disclosed
EP-1272144-A4 NEW COSMETIC, PERSONAL CARE, CLEANING AGENT, AND NUTRITIONAL SUPPLEMENT COMPOSITIONS COMPRISING BIOACTIVE GLASS AND METHODS OF MAKING AND USING THE SAME SCHOTT AG (DE) 2006-04-26 EP disclosed
CN-1671759-A Copolymers and their use in personal care compositions CIBA SC HOLDING AG (CH) 2005-09-21 CN disclosed
CN-1455661-A Novel cosmetic, personal care, detergent and nutritional supplement compositions containing bioactive glass and methods of making and using the same SCHOTT GLAS (DE) 2003-11-12 CN disclosed
EP-1272144-A2 NEW COSMETIC, PERSONAL CARE, CLEANING AGENT, AND NUTRITIONAL SUPPLEMENT COMPOSITIONS COMPRISING BIOACTIVE GLASS AND METHODS OF MAKING AND USING THE SAME Schott Glas (DE) 2003-01-08 EP disclosed
US-20020086039-A1 As preservative SCHOTT AG (DE) 2002-07-04 US disclosed
WO-2001072262-A2 NEW COSMETIC, PERSONAL CARE, CLEANING AGENT, AND NUTRITIONAL SUPPLEMENT COMPOSITIONS COMPRISING BIOACTIVE GLASS AND METHODS OF MAKING AND USING THE SAME SCHOTT GLAS (DE) 2001-10-04 WO disclosed