Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19626021 | 0.95 | CYP19A1 (0.68) | CYP19A1 | |
| SCHEMBL23223044 | 0.95 | CYP19A1 (0.68) | CYP19A1 | |
| SCHEMBL26860426 | 0.84 | CYP19A1 (0.63) | CYP19A1 | |
| SCHEMBL13046032 | 0.82 | CYP19A1 (0.72) | CYP19A1 | |
| SCHEMBL3744536 | 0.82 | CYP19A1 (0.72) | CYP19A1 | |
| SCHEMBL23514191 | 0.82 | AR (0.46) | CYP19A1 | |
| SCHEMBL19634768 | 0.82 | CYP19A1 (0.66) | CYP19A1 | |
| SCHEMBL20925993 | 0.82 | CYP19A1 (0.66) | CYP19A1 | |
| SCHEMBL23638378 | 0.82 | CYP17A1 (0.64) | CYP19A1 | |
| SCHEMBL29890992 | 0.82 | CYP17A1 (0.64) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848382-A1 | INTERMEDIATES FOR THE SYNTHESIS OF BILE ACID DERIVATIVES, IN PARTICULAR OF OBETICHOLIC ACID | NZP UK Limited (GB) | 2021-07-14 | — | — | EP | disclosed |
| EP-3458469-B1 | INTERMEDIATES FOR THE SYNTHESIS OF BILE ACID DERIVATIVES, IN PARTICULAR OF OBETICHOLIC ACID | NZP UK LTD (GB) | 2021-04-14 | — | — | EP | disclosed |
| WO-2017199033-A1 | INTERMEDIATES FOR THE SYNTHESIS OF BILE ACID DERIVATIVES, IN PARTICULAR OF OBETICHOLIC ACID | NZP UK Limited (GB) | 2017-11-23 | — | — | WO | disclosed |