Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 6/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | SHBG | P04278 | 4/20 | 0.63 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.63 |
| ▸ | PGR | P06401 | 3/20 | 0.63 |
| ▸ | AR | P10275 | 3/20 | 0.63 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.63 |
| ▸ | SNCA | P37840 | 2/20 | 0.63 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.63 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.63 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23638378 | 1.00 | CYP17A1 (0.64) | CYP17A1LMNACYP3A4MAPTHSD17B10 | |
| SCHEMBL19626004 | 1.00 | CYP17A1 (0.64) | CYP17A1LMNACYP3A4MAPTHSD17B10 | |
| SCHEMBL19626015 | 0.95 | CYP17A1 (0.64) | CYP17A1LMNACYP3A4MAPTHSD17B10 | |
| SCHEMBL11145349 | 0.87 | CYP19A1 (0.67) | CYP17A1LMNACYP3A4MAPTHSD17B10 | |
| SCHEMBL11572462 | 0.86 | CYP3A4 (0.70) | CYP17A1LMNACYP3A4MAPTHSD17B10 | |
| SCHEMBL19786466 | 0.86 | LMNA (0.63) | CYP17A1LMNACYP3A4MAPTHSD17B10 | |
| SCHEMBL28609896 | 0.84 | NPC1L1 (0.76) | CYP17A1LMNACYP3A4MAPTHSD17B10 | |
| SCHEMBL22475748 | 0.84 | LMNA (0.66) | CYP17A1LMNACYP3A4MAPTHSD17B10 | |
| SCHEMBL19635112 | 0.84 | CYP3A4 (0.69) | CYP17A1LMNACYP3A4MAPTHSD17B10 | |
| SCHEMBL21367235 | 0.84 | CYP3A4 (0.69) | CYP17A1LMNACYP3A4MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415404-B | Process and intermediates for 6, 7-alpha-epoxidation of steroid 4, 6-dienes | NZP英国有限公司 | 2022-08-26 | — | — | CN | disclosed |