SCHEMBL19628134

SCHEMBL19628134

c1ccc2cc(-c3ccc(-c4cc5cccc6c7c8ccccc8sc7c7cccc4c7c56)cc3)ccc2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
S1PR5 Q9H228 8/20 0.36
S1PR4 O95977 6/20 0.36
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
GSTP1 P09211 1/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
ERBB2 P04626 1/20 0.33
CYP1A2 P05177 1/20 0.33
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19628153 0.95 ALOX5 (0.41) ALOX5S1PR5S1PR4HSD17B1HSD17B2
SCHEMBL19628179 0.90 ALOX5 (0.38) ALOX5S1PR5S1PR4GSTP1TNKS
SCHEMBL19628161 0.90 GSTP1 (0.36) ALOX5ESR1ESR2S1PR5S1PR4
SCHEMBL19628158 0.89 LIMK1 (0.38) ESR1ESR2S1PR5S1PR4HSD17B1
SCHEMBL19628164 0.88 CA12 (0.37) ALOX5ESR1ESR2S1PR5S1PR4
SCHEMBL19628140 0.88 MEN1 (0.38) ALOX5TNKSTNKS2ERBB2CYP1A2
SCHEMBL19628160 0.88 ALOX5 (0.35) ALOX5S1PR5S1PR4HSD17B1HSD17B2
SCHEMBL19628185 0.87 ALOX5 (0.41) ALOX5S1PR5S1PR4TNKSTNKS2
SCHEMBL19628166 0.86 S1PR5 (0.39) ALOX5S1PR5S1PR4GSTP1TNKS
SCHEMBL19628146 0.84 TNKS (0.35) ALOX5HSD17B1HSD17B2TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439144-B2 Organic compound for electronic device comprising fused-core structure, organic optoelectronic device comprising same, and display device UNIVERSITY-INDUSTRY COOPERATEON GROUP OF KYUNG HEE UNIVERSITY (KR) 2019-10-08 US disclosed
US-20170338416-A1 ORGANIC COMPOUND FOR ELECTRONIC DEVICE COMPRISING FUSED-CORE STRUCTURE, ORGANIC OPTOELECTRONIC DEVICE COMPRISING SAME, AND DISPLAY DEVICE UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2017-11-23 US disclosed
US-20170338416-A1 ORGANIC COMPOUND FOR ELECTRONIC DEVICE COMPRISING FUSED-CORE STRUCTURE, ORGANIC OPTOELECTRONIC DEVICE COMPRISING SAME, AND DISPLAY DEVICE UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2017-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10439144-B2 Organic compound for electronic device comprising fused-core structure, organic optoelectronic device comprising same, and display device OR10J3, OCIAD2, OCIAD1 ALOX5 1129/4885ESR1 51/4885ESR2 297/4885
US-20170338416-A1 ORGANIC COMPOUND FOR ELECTRONIC DEVICE COMPRISING FUSED-CORE STRUCTURE, ORGANIC OPTOELECTRONIC DEVICE COMPRISING SAME, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 ALOX5 1129/4885ESR1 51/4885ESR2 297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.