Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397417 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL19206170 | 0.97 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL554201 | 0.97 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL7218925 | 0.97 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL12491699 | 0.97 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL2769803 | 0.97 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL12491551 | 0.97 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL12491604 | 0.97 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL19206235 | 0.97 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL19206259 | 0.97 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334831-A1 | Kinetic resolution of racemic hydroxy ester via asymmetric catalytic hydrogenation and application thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334831-A1 | Kinetic resolution of racemic hydroxy ester via asymmetric catalytic hydrogenation and application thereof | CYP8B1, CYP3A5, HRH4 | SMN1; SMN2 2704/4885LMNA 1184/4885ALDH1A1 2416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.