Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550254 | 1.00 | MAPK1 (0.48) | MAPK1CA1CA2CA7NOS1 | |
| SCHEMBL12171679 | 0.83 | MAPK1 (0.48) | MAPK1CA1CA2CA7CA12 | |
| SCHEMBL16508862 | 0.83 | MAPK1 (0.48) | MAPK1CA1CA2CA7CA12 | |
| SCHEMBL28485656 | 0.83 | CA1 (0.35) | MAPK1CA1CA2CA7NOS1 | |
| SCHEMBL14593924 | 0.79 | CA1 (0.38) | MAPK1CA1CA2CA7NOS1 | |
| SCHEMBL19628873 | 0.79 | PRKCA (0.47) | MAPK1CA1CA2CA7NOS1 | |
| SCHEMBL15354846 | 0.78 | CA14 (0.40) | CA1CA2CA7NOS1NOS3 | |
| SCHEMBL758635 | 0.78 | MEN1 (0.35) | MAPK1CA1CA2CA7NOS1 | |
| SCHEMBL16665545 | 0.77 | CA1 (0.37) | CA1CA2CA7NOS1NOS3 | |
| SCHEMBL12567766 | 0.77 | CA1 (0.37) | CA1CA2CA7NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170335059-A1 | FUNCTIONAL POLYMERS | THE UNIVERSITY OF AKRON | 2017-11-23 | — | — | US | disclosed |