Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17331173 | 0.98 | MAPK1 (0.59) | MAPK1HIF1AMAPTNPC1CA12 | |
| SCHEMBL21020731 | 0.98 | MAPK1 (0.59) | MAPK1HIF1AMAPTNPC1CA12 | |
| SCHEMBL15963822 | 0.98 | MAPK1 (0.59) | MAPK1HIF1AMAPTNPC1CA12 | |
| SCHEMBL15963820 | 0.98 | MAPK1 (0.59) | MAPK1HIF1AMAPTNPC1CA12 | |
| SCHEMBL15955780 | 0.98 | MAPK1 (0.59) | MAPK1HIF1AMAPTNPC1CA12 | |
| Hydrochloric Acid SCHEMBL30185779 | 0.97 | MAPK1 (0.57) | MAPK1HIF1AMAPTNPC1CA12 | |
| SCHEMBL22691913 | 0.95 | MAPK1 (0.59) | MAPK1HIF1AMAPTNPC1CA12 | |
| SCHEMBL22691906 | 0.93 | MAPK1 (0.64) | MAPK1HIF1AMAPTNPC1CA12 | |
| SCHEMBL17331184 | 0.90 | MAPK1 (0.75) | MAPK1HIF1AMAPTNPC1ALDH1A1 | |
| SCHEMBL17331183 | 0.90 | MAPK1 (0.75) | MAPK1HIF1AMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186548-B2 | Compounds for central reactivation of organophosphorus-based compound-inhibited acetylcholinesterase and/or inactivation of organophosphorus-based acetylcholinesterase inhibitors and related compositions methods and systems for making and using them | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2021-11-30 | — | — | US | disclosed |
| US-10590498-B2 | Compounds for reactivation of acetylcholinesterase and related compositions methods and systems | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2020-03-17 | — | — | US | disclosed |
| US-20190152920-A1 | COMPOUNDS FOR CENTRAL REACTIVATION OF ORGANOPHOSPHORUS- BASED COMPOUND-INHIBITED ACETYLCHOLINESTERASE AND/OR INACTIVATION OF ORGANOPHOSPHORUS-BASED ACETYLCHOLINESTERASE INHIBITORS AND RELATED COMPOSITIONS METHODS AND SYSTEMS FOR MAKING AND USING THEM | U.S. DEPARTMENT OF ENERGY | 2019-05-23 | — | — | US | disclosed |
| US-20170335415-A1 | COMPOUNDS FOR REACTIVATION OF ACETYLCHOLINESTERASE AND RELATED COMPOSITIONS METHODS AND SYSTEMS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152920-A1 | COMPOUNDS FOR CENTRAL REACTIVATION OF ORGANOPHOSPHORUS- BASED COMPOUND-INHIBITED ACETYLCHOLINESTERASE AND/OR INACTIVATION OF ORGANOPHOSPHORUS-BASED ACETYLCHOLINESTERASE INHIBITORS AND RELATED COMPOSITIONS METHODS AND SYSTEMS FOR MAKING AND USING THEM | ACHE, BCHE, CHAT | MAPK1 4072/4885HIF1A 4695/4885MAPT 1292/4885 |
| US-11186548-B2 | Compounds for central reactivation of organophosphorus-based compound-inhibited acetylcholinesterase and/or inactivation of organophosphorus-based acetylcholinesterase inhibitors and related compositions methods and systems for making and using them | ACHE, BCHE, CHAT | MAPK1 4072/4885HIF1A 4695/4885MAPT 1292/4885 |
| US-10590498-B2 | Compounds for reactivation of acetylcholinesterase and related compositions methods and systems | ACHE, BCHE, CHAT | MAPK1 4109/4885HIF1A 3528/4885MAPT 1384/4885 |
| US-20170335415-A1 | COMPOUNDS FOR REACTIVATION OF ACETYLCHOLINESTERASE AND RELATED COMPOSITIONS METHODS AND SYSTEMS | ACHE, BCHE, CHAT | MAPK1 4109/4885HIF1A 3528/4885MAPT 1384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.