Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 10/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332897 | 0.80 | NR3C2 (0.42) | NR3C2MMP12CYP11B1CYP11B2NR3C1 | |
| SCHEMBL1333452 | 0.80 | NR3C2 (0.42) | NR3C2MMP12CYP11B1CYP11B2NR3C1 | |
| SCHEMBL13089619 | 0.80 | NR3C2 (0.45) | NR3C2MMP12CYP11B1CYP11B2NR3C1 | |
| SCHEMBL20754037 | 0.78 | NR3C2 (0.43) | NR3C2MMP12NR3C1ALDH1A1MAPT | |
| SCHEMBL1378747 | 0.78 | NR3C2 (0.41) | NR3C2MMP12CYP11B1CYP11B2NR3C1 | |
| SCHEMBL22210583 | 0.76 | NR3C2 (0.42) | NR3C2MMP12CYP11B1CYP11B2NR3C1 | |
| SCHEMBL13425021 | 0.76 | NR3C2 (0.45) | NR3C2MMP12NR3C1ALDH1A1MAPT | |
| SCHEMBL21400859 | 0.75 | NR3C2 (0.47) | NR3C2MMP12NR3C1ALDH1A1MAPT | |
| SCHEMBL3435529 | 0.72 | CYP11B1 (0.38) | NR3C2MMP12CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL22509751 | 0.71 | NR3C2 (0.39) | NR3C2MMP12CYP11B1CYP11B2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017199265-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION | BUGWORKS RESEARCH INDIA PVT LTD (IN) | 2017-11-23 | — | — | WO | disclosed |