SCHEMBL1963027

SCHEMBL1963027

O=C(O)C1CC(C(=O)O)C(C(=O)O)C1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.58
CYP2C19 P33261 4/20 0.43
GABRR2 P28476 1/20 0.42
CYP2D6 P10635 3/20 0.40
SLC1A2 P43004 2/20 0.40
CYP1A2 P05177 2/20 0.40
ALOX15 P16050 2/20 0.40
SLC1A3 P43003 1/20 0.40
SLC1A1 P43005 1/20 0.40
ACE P12821 1/20 0.39
PMP22 Q01453 2/20 0.39
TSHR P16473 2/20 0.39
APLNR P35414 1/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3795818 0.97 GABRR1 (0.55) GABRR1CYP2C19GABRR2CYP2D6SLC1A2
Acetic Acid SCHEMBL11305422 0.91 GABRR1 (0.50) GABRR1CYP2C19GABRR2CYP2D6SLC1A2
SCHEMBL2019218 0.88 GABRR1 (0.52) GABRR1CYP2C19GABRR2SLC1A2SLC1A1
SCHEMBL28799 0.88 GABRR1 (0.52) GABRR1CYP2C19GABRR2SLC1A2SLC1A1
SCHEMBL21664518 0.88 GABRR1 (0.52) GABRR1CYP2C19GABRR2SLC1A2SLC1A1
SCHEMBL2019219 0.88 GABRR1 (0.52) GABRR1CYP2C19GABRR2SLC1A2SLC1A1
SCHEMBL9249263 0.88 GABRR1 (0.52) GABRR1CYP2C19GABRR2SLC1A2SLC1A1
SCHEMBL9721284 0.88 GABRR1 (0.52) GABRR1CYP2C19GABRR2SLC1A2SLC1A1
SCHEMBL16415207 0.87 GABRR1 (0.46) GABRR1CYP2C19GABRR2CYP2D6SLC1A2
SCHEMBL23394808 0.85 GABRR1 (0.50) GABRR1CYP2C19GABRR2CYP2D6SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11905381-B2 Polyimide microparticles XEROX CORPORATION (US) 2024-02-20 US claimed
CN-113072702-B Colorless transparent copolymerized polyimide film and preparation method thereof 上海大学(浙江·嘉兴)新兴产业研究院 2023-03-10 CN claimed
US-20220363843-A1 POLYIMIDE MICROPARTICLES XEROX CORPORATION (US) 2022-11-17 US claimed
EP-4089136-A1 POLYIMIDE MICROPARTICLES Xerox Corporation (US) 2022-11-16 EP claimed
CN-115322398-A Polyimide fine particles 施乐公司 2022-11-11 CN claimed
CN-103980489-B A kind of low melt viscosity thermoplastic polyimide material and its 3D printing forming method 中国科学院化学研究所 2018-08-31 CN claimed
EP-2708569-B1 TRANSPARENT POLYAMIDE-IMIDES EMS PATENT AG (CH) 2018-05-23 EP claimed
US-9422429-B2 Transparent polyamide-imides EMS-PATENT AG (CH) 2016-08-23 US claimed
US-20160222210-A1 TRANSPARENT POLYAMIDE-IMIDES EMS-PATENT AG (CH) 2016-08-04 US claimed
EP-2708569-A1 Transparent polyamidimide EMS-PATENT AG (CH) 2014-03-19 EP claimed
US-20140072745-A1 TRANSPARENT POLYAMIDE-IMIDES EMS-PATENT AG (CH) 2014-03-13 US claimed
EP-2398758-A1 REACTIVE EXTRACTION OF FREE ORGANIC ACIDS FROM AMMONIUM SALTS THEREOF Evonik Degussa GmbH (DE) 2011-12-28 EP claimed
EP-2398757-A1 METHOD FOR PRODUCING A FREE ACID FROM THE SALT THEREOF Evonik Degussa GmbH (DE) 2011-12-28 EP claimed
WO-2010094554-A1 METHOD FOR PRODUCING A FREE ACID FROM THE SALT THEREOF EVONIK DEGUSSA GMBH (DE) 2010-08-26 WO claimed
WO-2010094630-A1 REACTIVE EXTRACTION OF FREE ORGANIC ACIDS FROM AMMONIUM SALTS THEREOF EVONIK DEGUSSA GMBH (DE) 2010-08-26 WO claimed
US-20100210871-A1 Reactive Extraction of Free Organic Acids from the Ammonium Salts Thereof EVONIK DEGUSSA GMBH (DE) 2010-08-19 US claimed
US-4271032-A Polycarboxylic acids and esters in detergent formulations and their use TEXACO INC. (US) 1981-06-02 US claimed
JP-5201918-A None JP disclosed
EP-0273012-A2 Method of bonding CIBA-GEIGY AG (CH) 1988-06-29 EP disclosed
US-4271032-A Polycarboxylic acids and esters in detergent formulations and their use TEXACO INC. (US) 1981-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210871-A1 Reactive Extraction of Free Organic Acids from the Ammonium Salts Thereof CA2, HCN2, CA9 GABRR1 3656/4885CYP2C19 2267/4885GABRR2 3652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.