Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 14/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | NCS1 | P62166 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631005 | 0.87 | CSNK1D (0.55) | CSNK1DDYRK1AACP1CASP3SENP8 | |
| SCHEMBL19612122 | 0.86 | DYRK1A (0.57) | CSNK1DDYRK1AACP1NCS1CYP2D6 | |
| SCHEMBL24044916 | 0.84 | DYRK1A (0.54) | CSNK1DDYRK1AACP1CASP3SENP8 | |
| SCHEMBL19612108 | 0.84 | DYRK1A (0.54) | CSNK1DDYRK1AACP1CASP3SENP8 | |
| SCHEMBL19612156 | 0.83 | CSNK1D (0.50) | CSNK1DDYRK1AACP1NCS1CYP2D6 | |
| SCHEMBL19612166 | 0.83 | DYRK1A (0.53) | CSNK1DDYRK1AACP1NCS1CYP2D6 | |
| SCHEMBL19612165 | 0.83 | DYRK1A (0.53) | CSNK1DDYRK1AACP1CASP3SENP8 | |
| SCHEMBL19627267 | 0.83 | DYRK1A (0.53) | CSNK1DDYRK1AACP1CASP3SENP8 | |
| SCHEMBL19630876 | 0.82 | DYRK1A (0.51) | CSNK1DDYRK1AACP1CASP3SENP8 | |
| SCHEMBL19627268 | 0.81 | DYRK1A (0.48) | CSNK1DDYRK1AACP1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201313-A1 | NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | JIN SHENGKAN (US) | 2017-11-23 | — | — | WO | disclosed |