Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 12/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.52 |
| ▸ | FES | P07332 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.52 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.52 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.52 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.52 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17770524 | 0.90 | KDM4E (0.55) | CSNK1DKDM4EGAANPSR1RXFP1 | |
| SCHEMBL19612158 | 0.89 | KDM4E (0.54) | CSNK1DKDM4EGAANPSR1RXFP1 | |
| SCHEMBL19630998 | 0.87 | CSNK1D (0.50) | CSNK1DDYRK1ANCS1ACP1CASP3 | |
| SCHEMBL17770327 | 0.86 | KDM4E (0.69) | CSNK1DKDM4EGAANPSR1RXFP1 | |
| SCHEMBL24044886 | 0.83 | CSNK1D (0.56) | CSNK1DKDM4EGAANPSR1RXFP1 | |
| SCHEMBL19630768 | 0.81 | CSNK1D (0.55) | CSNK1DKDM4EGAANPSR1RXFP1 | |
| SCHEMBL19612089 | 0.81 | KDM4E (0.50) | CSNK1DKDM4EGAANPSR1RXFP1 | |
| SCHEMBL30472744 | 0.80 | CSNK1D (0.62) | CSNK1DDYRK1AMAP4K5ACP1 | |
| SCHEMBL17770389 | 0.80 | CSNK1D (0.62) | CSNK1DDYRK1AMAP4K5ACP1 | |
| SCHEMBL19612090 | 0.80 | LRRK2 (0.59) | CSNK1DKDM4EGAANPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201313-A1 | NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | JIN SHENGKAN (US) | 2017-11-23 | — | — | WO | disclosed |