Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | ADH1B | P00325 | 2/20 | 0.44 |
| ▸ | ADH1C | P00326 | 2/20 | 0.44 |
| ▸ | ADH1A | P07327 | 2/20 | 0.44 |
| ▸ | ADH4 | P08319 | 2/20 | 0.44 |
| ▸ | ADH7 | P40394 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21952707 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRACE2ADH1BADH1C | |
| SCHEMBL18521762 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRACE2ADH1BADH1C | |
| SCHEMBL21695004 | 0.96 | TSHR (0.50) | ALDH1A1TSHRACE2ADH1BADH1C | |
| SCHEMBL18721219 | 0.96 | TSHR (0.62) | ALDH1A1TSHRACE2ADH1BADH1C | |
| SCHEMBL12479972 | 0.96 | TSHR (0.62) | ALDH1A1TSHRACE2ADH1BADH1C | |
| SCHEMBL12478863 | 0.96 | TSHR (0.62) | ALDH1A1TSHRACE2ADH1BADH1C | |
| SCHEMBL18615410 | 0.96 | TSHR (0.62) | ALDH1A1TSHRACE2ADH1BADH1C | |
| SCHEMBL20427541 | 0.96 | TSHR (0.62) | ALDH1A1TSHRACE2ADH1BADH1C | |
| SCHEMBL24653400 | 0.93 | TSHR (0.59) | ALDH1A1TSHRACE2ADH1BADH1C | |
| SCHEMBL20130405 | 0.93 | TSHR (0.59) | ALDH1A1TSHRACE2ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201325-A1 | COMBINATIONS OF MRNAS ENCODING IMMUNE MODULATING POLYPEPTIDES AND USES THEREOF | MODERNATX, INC. (US) | 2017-11-23 | — | — | WO | disclosed |