Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 14/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MYLK | Q15746 | 1/20 | 0.47 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612094 | 0.89 | TMPRSS4 (0.52) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL19612095 | 0.89 | TMPRSS4 (0.57) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL17770319 | 0.88 | TMPRSS4 (0.55) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL31237407 | 0.88 | TMPRSS4 (0.55) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL19627231 | 0.86 | P2RX1 (0.53) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL19627233 | 0.86 | MAPT (0.58) | TMPRSS4P2RX1MEN1KMT2AKCNMA1 | |
| SCHEMBL19627237 | 0.86 | KDM4E (0.46) | TMPRSS4MEN1KMT2ACASP3SENP7 | |
| Monoethanolamine SCHEMBL19612104 | 0.82 | TMPRSS4 (0.48) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL19612110 | 0.80 | TMPRSS4 (0.57) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL19627243 | 0.78 | NPC1 (0.63) | MEN1KMT2AMAP4K5CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201313-A1 | NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | JIN SHENGKAN (US) | 2017-11-23 | — | — | WO | disclosed |