Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19825307 | 0.91 | RECQL (0.50) | RECQLALDH1A1CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL13274138 | 0.83 | RECQL (0.48) | RECQLALDH1A1CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL19687601 | 0.81 | RECQL (0.42) | RECQLALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1847539 | 0.79 | RECQL (0.49) | RECQLALDH1A1CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL16476083 | 0.78 | ABCG2 (0.41) | RECQLALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL19825281 | 0.78 | RECQL (0.40) | RECQLALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL18535350 | 0.78 | RECQL (0.51) | RECQLALDH1A1CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL19494991 | 0.78 | RECQL (0.42) | RECQLALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL24799971 | 0.77 | ALDH1A1 (0.41) | RECQLALDH1A1CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL6743766 | 0.77 | RECQL (0.50) | RECQLALDH1A1CYP3A4CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458111-B1 | PET-IMAGING IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-3702367-A1 | NOVEL PD-L1 BINDING POLYPEPTIDES FOR IMAGING | Bristol-Myers Squibb Company (US) | 2020-09-02 | — | — | EP | disclosed |
| WO-2017210302-A1 | PET IMAGING WITH PD-L1 BINDING POLYPEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017201111-A1 | PET-IMAGING IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-11-23 | — | — | WO | disclosed |