Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.69 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.69 |
| ▸ | MEF2D | Q14814 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631296 | 0.87 | KDM4E (0.69) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL19631377 | 0.85 | HDAC6 (0.69) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL3581803 | 0.83 | RAB9A (0.71) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL3581806 | 0.83 | RAB9A (0.71) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL3918321 | 0.82 | HDAC1 (0.66) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL3918320 | 0.82 | HDAC1 (0.66) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL19616809 | 0.81 | HDAC6 (1.00) | HDAC6KDM4EALDH1A1LMNARAB9A | |
| SCHEMBL21356567 | 0.81 | KDR (0.67) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL19631304 | 0.81 | KDR (0.67) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL9093698 | 0.77 | HDAC6 (0.67) | HDAC6KDM4EALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346563-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | UNIV TAIPEI MEDICAL (TW) | 2025-11-13 | — | — | US | disclosed |
| US-11427544-B2 | Histone deacetylase 6 inhibitors and use thereof | TAIPEI MEDICAL UNIVERSITY (TW) | 2022-08-30 | — | — | US | disclosed |
| US-20220251043-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | TAIPEI MEDICAL UNIVERSITY (TW) | 2022-08-11 | — | — | US | disclosed |
| EP-3458444-B1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | UNIV TAIPEI MEDICAL (TW) | 2022-06-22 | — | — | EP | disclosed |
| EP-3458444-B1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | UNIV TAIPEI MEDICAL (TW) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021013163-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | TAIPEI MEDICAL UNIVERSITY (CN) | 2021-01-28 | — | — | WO | disclosed |
| US-20190284141-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | DCB-USA LLC (US) | 2019-09-19 | — | — | US | disclosed |
| US-20190284141-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | DCB-USA LLC (US) | 2019-09-19 | — | — | US | disclosed |
| WO-2017200966-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | DCB-USA LLC (US) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190284141-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | HDAC1, HDAC11, HDAC7 | HDAC6 7/4885HDAC1 1/4885HDAC2 4/4885 |
| US-20250346563-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | HDAC1, HDAC3, HDAC5 | HDAC6 4/4885HDAC1 1/4885HDAC2 6/4885 |
| US-20220251043-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | HDAC1, HDAC3, HDAC2 | HDAC6 9/4885HDAC1 1/4885HDAC2 3/4885 |
| US-11427544-B2 | Histone deacetylase 6 inhibitors and use thereof | HDAC1, HDAC11, HDAC7 | HDAC6 7/4885HDAC1 1/4885HDAC2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.