Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19627580 | 0.94 | P2RY12 (0.39) | ADORA3P2RY12PRMT6ADORA1ADORA2A | |
| SCHEMBL19627581 | 0.94 | P2RY12 (0.39) | ADORA3P2RY12PRMT6ADORA1ADORA2A | |
| SCHEMBL17775275 | 0.94 | P2RY12 (0.39) | ADORA3P2RY12PRMT6ADORA1ADORA2A | |
| SCHEMBL17775276 | 0.94 | P2RY12 (0.39) | ADORA3P2RY12PRMT6ADORA1ADORA2A | |
| SCHEMBL20089175 | 0.90 | P2RY12 (0.36) | ADORA3P2RY12PRMT6ADORA1ADORA2A | |
| SCHEMBL20089176 | 0.90 | P2RY12 (0.36) | ADORA3P2RY12PRMT6ADORA1ADORA2A | |
| SCHEMBL19407882 | 0.89 | ADORA3 (0.40) | ADORA3P2RY12PRMT6ADORA1 | |
| SCHEMBL16902707 | 0.84 | ADORA3 (0.36) | ADORA3P2RY12PRMT6ADORA1 | |
| SCHEMBL16940124 | 0.84 | ADORA3 (0.36) | ADORA3P2RY12PRMT6ADORA1 | |
| SCHEMBL16902693 | 0.84 | ADORA3 (0.36) | ADORA3P2RY12PRMT6ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170335323-A1 | Chiral Library Screen | ROCHE INNOVATION CENTER COPENHAGEN A/S (CH) | 2017-11-23 | — | — | US | disclosed |