Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 4/20 | 0.48 |
| ▸ | ELOVL1 | Q9BW60 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23862490 | 0.87 | MAPT (0.46) | CASRELOVL1MAPTHTTTSHR | |
| SCHEMBL17239541 | 0.85 | CASR (0.46) | CASRELOVL1MAPTHTTTSHR | |
| SCHEMBL2609420 | 0.82 | CASR (0.48) | CASRELOVL1MAPTHTTTSHR | |
| SCHEMBL1063156 | 0.81 | ELOVL1 (0.47) | CASRELOVL1MAPTHTTTSHR | |
| SCHEMBL22169568 | 0.79 | CASR (0.43) | CASRELOVL1MAPTHTTTSHR | |
| SCHEMBL13951863 | 0.78 | NOTUM (0.37) | CASRHSD17B10CYP2C9 | |
| SCHEMBL18191176 | 0.75 | CASR (0.52) | CASRELOVL1MAPTHTTTSHR | |
| SCHEMBL8953901 | 0.74 | CASR (0.44) | CASRELOVL1MAPTHTTTSHR | |
| SCHEMBL18713691 | 0.72 | KMT2A (0.36) | HTTTSHR | |
| SCHEMBL25464805 | 0.72 | KMT2A (0.36) | HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198339-A1 | TETRAHYDROPYRAN AND THIOPYRAN DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2017-11-23 | — | — | WO | disclosed |