Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PPP5C | P53041 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.38 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890089 | 0.83 | CYP1A2 (0.44) | CYP1A2TDP1HTTLMNAHRH3 | |
| SCHEMBL25511901 | 0.82 | ALDH1A1 (0.47) | HTTHRH3ALDH1A1 | |
| SCHEMBL25498169 | 0.80 | HTT (0.70) | CYP1A2TDP1HTTLMNAALDH1A1 | |
| SCHEMBL25498347 | 0.80 | HTT (0.70) | CYP1A2TDP1HTTLMNAALDH1A1 | |
| SCHEMBL25499141 | 0.80 | HTT (0.55) | CYP1A2TDP1HTTLMNAALDH1A1 | |
| SCHEMBL5470776 | 0.80 | CYP1A2 (0.65) | CYP1A2TDP1HTTLMNANPSR1 | |
| SCHEMBL18390873 | 0.79 | CYP1A2 (0.48) | CYP1A2TDP1HTTLMNAHRH3 | |
| SCHEMBL18390876 | 0.79 | CYP1A2 (0.48) | CYP1A2TDP1HTTLMNAHRH3 | |
| SCHEMBL13779985 | 0.79 | ALDH1A1 (0.48) | CYP1A2TDP1HTTLMNAHRH3 | |
| SCHEMBL12639932 | 0.78 | MEN1 (0.53) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170333567-A1 | Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers | SYNTARGA BV (NL) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170333567-A1 | Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers | PCNA, DCLRE1A, CDC5L | CYP1A2 4008/4885TDP1 290/4885HTT 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.