Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bisoctrizole SCHEMBL29358089 | 0.95 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBIDH1 | |
| Bisoctrizole SCHEMBL39191 | 0.95 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBIDH1 | |
| Bisoctrizole SCHEMBL30113083 | 0.95 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBIDH1 | |
| Bisoctrizole SCHEMBL5994392 | 0.95 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBIDH1 | |
| SCHEMBL30545220 | 0.93 | NPC1 (0.39) | NPC1RAB9ALMNAPOLBIDH1 | |
| SCHEMBL8962738 | 0.92 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBIDH1 | |
| SCHEMBL14198250 | 0.92 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBIDH1 | |
| SCHEMBL9314160 | 0.92 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBIDH1 | |
| Bisoctrizole SCHEMBL28644655 | 0.91 | IDH1 (0.41) | NPC1RAB9ALMNAPOLBIDH1 | |
| SCHEMBL8204058 | 0.90 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198806-A1 | MICRO-PARTICULATE ORGANIC UV ABSORBER COMPOSITION | BASF SE (DE) | 2017-11-23 | — | — | WO | disclosed |