SCHEMBL8204058

SCHEMBL8204058

Cc1cc(C(C)(C)CC(C)(C)C)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.48
RAB9A P51151 7/20 0.48
LMNA P02545 1/20 0.44
POLB P06746 3/20 0.43
SHBG P04278 1/20 0.38
IDH1 O75874 1/20 0.38
KDM4E B2RXH2 5/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
ALDH1A1 P00352 6/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
CYP3A4 P08684 2/20 0.35
HIF1A Q16665 2/20 0.35
ALOX15 P16050 2/20 0.35
HSD17B10 Q99714 2/20 0.35
CYP2C9 P11712 1/20 0.35
MAPT P10636 5/20 0.35
HPGD P15428 4/20 0.35
TDP1 Q9NUW8 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19633285 0.90 NPC1 (0.42) NPC1RAB9ALMNAPOLBSHBG
SCHEMBL7570384 0.89 NPC1 (0.45) NPC1RAB9ALMNAPOLBSHBG
SCHEMBL18375140 0.89 NPC1 (0.45) NPC1RAB9ALMNAPOLBSHBG
SCHEMBL673358 0.88 NPC1 (0.44) NPC1RAB9ALMNAPOLBSHBG
SCHEMBL29371482 0.88 NPC1 (0.44) NPC1RAB9ALMNAPOLBSHBG
SCHEMBL28904542 0.88 NPC1 (0.42) NPC1RAB9ALMNAPOLBSHBG
Bisoctrizole SCHEMBL30113083 0.87 NPC1 (0.43) NPC1RAB9ALMNAPOLBSHBG
SCHEMBL105823 0.87 NPC1 (0.43) NPC1RAB9ALMNAPOLBSHBG
SCHEMBL22369627 0.87 NPC1 (0.43) NPC1RAB9ALMNAPOLBSHBG
SCHEMBL18375109 0.87 NPC1 (0.43) NPC1RAB9ALMNAPOLBSHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3196253-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF MITSUBISHI CHEM CORP (JP) 2024-10-09 EP disclosed
EP-3488287-B1 PRINTING INK, PREFERABLY 3D PRINTING INK, SPECTACLE LENS, AND METHOD FOR MANUFACTURING AN EYEGLASS LENS ZEISS CARL VISION INT GMBH (DE) 2023-12-20 EP disclosed
CN-111171545-B Polycarbonate resin composition, method for producing same, and molded article 三菱化学株式会社 2023-04-28 CN disclosed
EP-2594608-B1 POLYCARBONATE RESIN COMPOSITION, AND MOLDED ARTICLE, FILM, PLATE AND INJECTION-MOLDED ARTICLE EACH COMPRISING SAME MITSUBISHI CHEM CORP (JP) 2022-11-16 EP disclosed
CN-113383048-A Antireflection film with adhesive layer, self-luminous display device, and method for producing same 日东电工株式会社 2021-09-10 CN disclosed
CN-108203539-B Interior or exterior member for automobile and outboard motor part 铃木株式会社 2021-01-12 CN disclosed
EP-3318603-B1 POLYCARBONATE RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND MOLDED OBJECT MITSUBISHI CHEM CORP (JP) 2020-11-18 EP disclosed
CN-108603018-B Polycarbonate resin composition and molded article thereof 三菱化学株式会社 2020-08-14 CN disclosed
CN-107849344-B Polycarbonate resin compound 华东理工大学 2020-07-10 CN disclosed
CN-107922720-B Polycarbonate resin composition, method for producing same, and molded article 华东理工大学 2020-06-19 CN disclosed
US-20140031494-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2014-01-30 US disclosed
CN-103476868-A Polycarbonate resin composition and molded article thereof MITSUBISHI CHEM CORP 2013-12-25 CN disclosed
CN-103459499-A Polycarbonate resin composition and molded article thereof MITSUBISHI CHEM CORP 2013-12-18 CN disclosed
EP-1064922-B9 Photoprotective compositions containing a bis-hydroxyphenylbenzotriazole compound and a compound having benzoazolyl or benzodiazolyl groups OREAL (FR) 2009-08-12 EP disclosed
US-7358015-B2 Plasticized photoconductor LEXMARK INTERNATIONAL, INC. (US) 2008-04-15 US disclosed
EP-1062943-B1 Cosmetic or dermatologic sunscreen compositions containing boron nitride and UV filters having triazine groups BEIERSDORF AG (DE) 2008-01-09 EP disclosed
EP-1004290-A2 Cosmetic or pharmaceutical compositions containing 1,3,5-triazinderivatives and zinc oxide BASF AKTIENGESELLSCHAFT (DE) 2000-05-31 EP disclosed
EP-0935528-A1 UV STABILIZED MULTI-LAYER STRUCTURES WITH DETECTABLE UV PROTECTIVE LAYERS AND A METHOD OF DETECTION EASTMAN CHEMICAL COMPANY (US) 1999-08-18 EP disclosed
WO-1998019862-A1 UV STABILIZED MULTI-LAYER STRUCTURES WITH DETECTABLE UV PROTECTIVE LAYERS AND A METHOD OF DETECTION EASTMAN CHEMICAL COMPANY (US) 1998-05-14 WO disclosed
US-5051460-A Chlorotrifluoroethylene-ethylene copolymer with heat resistant stabilizers, epoxy resins, phosphites and esters AUSIMONT, U.S.A., INC. (US) 1991-09-24 US disclosed