Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633361 | 0.93 | TLR7 (0.49) | TLR7NUDT1 | |
| SCHEMBL19633365 | 0.88 | TLR7 (0.45) | TLR7NUDT1 | |
| SCHEMBL19633466 | 0.88 | TLR7 (0.47) | TLR7NUDT1PNP | |
| SCHEMBL3920579 | 0.84 | TLR7 (0.45) | TLR7NUDT1 | |
| SCHEMBL19633585 | 0.83 | TLR7 (0.47) | TLR7NUDT1 | |
| SCHEMBL3995288 | 0.82 | TLR7 (0.47) | TLR7NUDT1 | |
| SCHEMBL19633360 | 0.81 | TLR7 (0.48) | TLR7NUDT1 | |
| SCHEMBL23638053 | 0.81 | TLR7 (0.53) | TLR7NUDT1 | |
| SCHEMBL23331426 | 0.81 | TLR7 (0.52) | TLR7NUDT1 | |
| SCHEMBL19633387 | 0.81 | TLR7 (0.46) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197624-A1 | PURINE-SCAFFOLD TLR7 LIGANDS AND CONJUGATE THEREOF | SHENZHEN HORNETCORN BIOTECHNOLOGY COMPANY,CO., LTD (CN) | 2017-11-23 | — | — | WO | disclosed |