Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633466 | 0.93 | TLR7 (0.47) | TLR7NUDT1ADORA2AADORA2BADORA1 | |
| SCHEMBL19633361 | 0.87 | TLR7 (0.49) | TLR7NUDT1KMO | |
| SCHEMBL19633306 | 0.81 | TLR7 (0.47) | TLR7NUDT1 | |
| SCHEMBL3930476 | 0.79 | TLR7 (0.44) | TLR7NUDT1ADORA2AADORA2BADORA1 | |
| SCHEMBL19633363 | 0.78 | TLR7 (0.44) | TLR7NUDT1 | |
| SCHEMBL19633585 | 0.78 | TLR7 (0.47) | TLR7NUDT1 | |
| SCHEMBL4102681 | 0.78 | TLR7 (0.43) | TLR7NUDT1ADORA2AADORA2BADORA1 | |
| SCHEMBL509587 | 0.77 | TLR7 (0.74) | TLR7NUDT1ADORA2AADORA1 | |
| SCHEMBL4102688 | 0.77 | TLR7 (0.41) | TLR7NUDT1ADORA2AADORA2BADORA1 | |
| SCHEMBL3930482 | 0.77 | TLR7 (0.42) | TLR7NUDT1ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197624-A1 | PURINE-SCAFFOLD TLR7 LIGANDS AND CONJUGATE THEREOF | SHENZHEN HORNETCORN BIOTECHNOLOGY COMPANY,CO., LTD (CN) | 2017-11-23 | — | — | WO | disclosed |