Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12003956 | 0.88 | PDGFRA (0.53) | PDGFRAKDRMAPTHTTPOLB | |
| SCHEMBL15537365 | 0.85 | KDR (0.63) | PDGFRAKDRMET | |
| SCHEMBL12003971 | 0.83 | KDR (0.53) | PDGFRAKDRMAPTHTTPOLB | |
| SCHEMBL12003969 | 0.83 | KDR (0.53) | PDGFRAKDRMAPTHTTPOLB | |
| SCHEMBL12004518 | 0.83 | KDR (0.53) | PDGFRAKDRMET | |
| SCHEMBL12003929 | 0.82 | CTSV (0.50) | PDGFRAKDRMAPTNPC1RAB9A | |
| SCHEMBL29453859 | 0.81 | PDGFRA (0.54) | PDGFRAKDRMAPTRAB9AHTT | |
| SCHEMBL7461377 | 0.81 | PDGFRA (0.54) | PDGFRAKDRMAPTHTTMAPK1 | |
| SCHEMBL22749989 | 0.81 | PDGFRA (0.54) | PDGFRAKDRMAPTRAB9AHTT | |
| SCHEMBL12004509 | 0.81 | PDGFRA (0.57) | PDGFRAKDRMAPTRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |