Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 3/20 | 0.81 |
| ▸ | EGFR | P00533 | 10/20 | 0.78 |
| ▸ | GAK | O14976 | 2/20 | 0.67 |
| ▸ | FADS1 | O60427 | 1/20 | 0.54 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633642 | 0.89 | EGFR (0.71) | ALKEGFRGAKFADS1PKMYT1 | |
| SCHEMBL19633716 | 0.89 | ALK (0.72) | ALKEGFRGAKFADS1PKMYT1 | |
| SCHEMBL19633659 | 0.89 | ALK (0.72) | ALKEGFRGAKFADS1PKMYT1 | |
| SCHEMBL4738872 | 0.88 | EGFR (1.00) | ALKEGFRGAKFADS1 | |
| SCHEMBL19633634 | 0.85 | EGFR (0.72) | ALKEGFRGAK | |
| SCHEMBL28845712 | 0.85 | EGFR (0.66) | ALKEGFRGAKFADS1 | |
| SCHEMBL19633677 | 0.85 | ALK (0.67) | ALKEGFRGAKRET | |
| SCHEMBL7618830 | 0.84 | EGFR (0.68) | ALKEGFRGAKFADS1PKMYT1 | |
| SCHEMBL19633704 | 0.83 | PTK6 (0.66) | ALKEGFRGAK | |
| SCHEMBL19633507 | 0.81 | EGFR (0.60) | ALKEGFRGAKFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |