SCHEMBL19633929

SCHEMBL19633929

CN(c1cc(F)c(SNc2nccs2)cc1Cl)C1CCN(Cc2ccccc2)CC1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 19/20 0.70
SCN1A P35498 14/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19612980 0.83 SCN8A (1.00) SCN8ASCN1A
SCHEMBL19634082 0.82 SCN8A (0.69) SCN8ASCN1A
SCHEMBL19634042 0.79 SCN8A (0.71) SCN8ASCN1A
SCHEMBL19627618 0.78 SCN8A (1.00) SCN8ASCN1A
SCHEMBL28532421 0.78 SCN8A (1.00) SCN8ASCN1A
SCHEMBL19634015 0.76 SCN8A (0.62) SCN8ASCN1A
SCHEMBL20256165 0.75 SCN8A (0.50) SCN8ASCN1A
Trifluoroacetic Acid SCHEMBL19613291 0.74 SCN8A (0.90) SCN8ASCN1A
Trifluoroacetic Acid SCHEMBL29447394 0.74 SCN8A (0.90) SCN8ASCN1A
SCHEMBL20256570 0.73 LMNA (0.43) SCN8ASCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017201468-A1 BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2017-11-23 WO disclosed