Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 17/20 | 0.67 |
| ▸ | SCN1A | P35498 | 16/20 | 0.67 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633981 | 0.93 | SCN8A (0.69) | SCN8ASCN1A | |
| SCHEMBL19634306 | 0.81 | SCN8A (0.67) | SCN8ASCN1A | |
| SCHEMBL19634122 | 0.81 | SCN8A (0.66) | SCN8ASCN1AUBE2MDCUN1D1SCN5A | |
| SCHEMBL19613000 | 0.80 | SCN8A (1.00) | SCN8ASCN1ASCN5A | |
| SCHEMBL20256404 | 0.78 | SCN8A (0.43) | SCN8ASCN1ASCN5A | |
| SCHEMBL19634194 | 0.78 | SCN1A (0.69) | SCN8ASCN1AHRH1UBE2MDCUN1D1 | |
| SCHEMBL20256591 | 0.76 | SCN8A (0.64) | SCN8ASCN1ASCN5A | |
| SCHEMBL20256562 | 0.76 | SCN8A (0.64) | SCN8ASCN1ASCN5A | |
| Trifluoroacetic Acid SCHEMBL19613763 | 0.75 | SCN8A (0.88) | SCN8ASCN1ASCN5A | |
| SCHEMBL19634001 | 0.75 | SCN8A (0.66) | SCN8ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |