SCHEMBL19634306

SCHEMBL19634306

CC1(Nc2ccc(SNc3cscn3)cc2Cl)CN(Cc2ccccc2)C1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 20/20 0.67
SCN1A P35498 17/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19634017 0.81 SCN8A (0.67) SCN8ASCN1A
SCHEMBL19613223 0.80 SCN8A (1.00) SCN8ASCN1A
SCHEMBL19634007 0.79 SCN8A (0.69) SCN8ASCN1A
SCHEMBL19634138 0.78 SCN8A (0.61) SCN8ASCN1A
SCHEMBL20256251 0.78 SCN1A (0.41) SCN8ASCN1A
SCHEMBL19633981 0.75 SCN8A (0.69) SCN8ASCN1A
Trifluoroacetic Acid SCHEMBL19613704 0.75 SCN8A (0.88) SCN8ASCN1A
SCHEMBL19614292 0.74 SCN8A (1.00) SCN8ASCN1A
SCHEMBL19613430 0.74 SCN8A (1.00) SCN8ASCN1A
SCHEMBL19613019 0.74 SCN8A (1.00) SCN8ASCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017201468-A1 BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2017-11-23 WO disclosed