Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.42 |
| ▸ | SCN1A | P35498 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634144 | 0.88 | SCN8A (0.51) | SCN8ASCN1AGAATSHR | |
| SCHEMBL19631790 | 0.83 | SCN8A (0.51) | SCN8ASCN1A | |
| SCHEMBL19634068 | 0.77 | MEN1 (0.38) | GAATSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL19634129 | 0.75 | SCN8A (0.47) | SCN8ASCN1ASIGMAR1GAATSHR | |
| SCHEMBL19634331 | 0.73 | SCN8A (0.52) | SCN8ASCN1A | |
| SCHEMBL19631649 | 0.73 | SCN8A (0.51) | SCN8ASCN1A | |
| SCHEMBL19633913 | 0.72 | SCN8A (0.49) | SCN8ASCN1ASMN1; SMN2GAASCN9A | |
| SCHEMBL19634127 | 0.72 | SCN8A (0.48) | SCN8ASCN1ASIGMAR1GAAKMT2A | |
| SCHEMBL19614231 | 0.72 | SCN8A (0.61) | SCN8ASCN1A | |
| SCHEMBL19613503 | 0.72 | SCN8A (0.61) | SCN8ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |