Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 19/20 | 0.52 |
| ▸ | SCN1A | P35498 | 11/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634144 | 0.85 | SCN8A (0.51) | SCN8ASCN1AHRH3 | |
| SCHEMBL19613482 | 0.84 | SCN8A (0.62) | SCN8ASCN1A | |
| SCHEMBL19613481 | 0.84 | SCN8A (0.62) | SCN8ASCN1A | |
| SCHEMBL19627759 | 0.77 | SCN8A (0.63) | SCN8ASCN1A | |
| SCHEMBL19634143 | 0.77 | SCN8A (0.51) | SCN8ASCN1A | |
| SCHEMBL19633903 | 0.77 | MEN1 (0.40) | — | |
| SCHEMBL19634035 | 0.75 | SCN8A (0.68) | SCN8ASCN1A | |
| SCHEMBL19634053 | 0.73 | SCN8A (0.42) | SCN8ASCN1A | |
| SCHEMBL19613505 | 0.72 | SCN8A (0.61) | SCN8ASCN1A | |
| SCHEMBL19613503 | 0.72 | SCN8A (0.61) | SCN8ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |