Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 19/20 | 0.61 |
| ▸ | SCN1A | P35498 | 11/20 | 0.61 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634239 | 0.93 | SCN8A (0.71) | SCN8ASCN1ASCN9A | |
| SCHEMBL19634062 | 0.93 | SCN8A (0.70) | SCN8ASCN1A | |
| SCHEMBL19627595 | 0.83 | SCN8A (0.87) | SCN8ASCN1ASCN9A | |
| SCHEMBL19634142 | 0.79 | SCN8A (0.67) | SCN8ASCN1A | |
| SCHEMBL19634146 | 0.78 | SCN8A (0.67) | SCN8ASCN1ASCN9A | |
| Trifluoroacetic Acid SCHEMBL19613766 | 0.77 | SCN8A (0.79) | SCN8ASCN1A | |
| SCHEMBL19627596 | 0.76 | SCN8A (1.00) | SCN8ASCN1A | |
| SCHEMBL19627594 | 0.75 | SCN8A (1.00) | SCN8ASCN1A | |
| Trifluoroacetic Acid SCHEMBL19613622 | 0.71 | SCN8A (0.88) | SCN8ASCN1A | |
| SCHEMBL19634051 | 0.71 | SCN8A (0.67) | SCN8ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |